The 53-year-old Dortmund chief believes the club will announce record figures for the full financial year, but says Klopp will still need to work within a sustainable budget
The German giants are due to release their results for the first six months of the financial year on Monday and, despite the club enduring a difficult domestic campaign at the Westfalenstadion this season, Watzke believes matters off-the-field will soon prompt cause to celebrate.
Speaking to Bild Am Sonntag, the 53-year-old said: "I hope that for the full year we manage to make more than €250m for the first time.
"So far in the Bundesliga, Bayern are the only club to record figures that substantial. In 2005, when I arrived at the club, the figure was just €87 million."
But Watzke also said coach Jurgen Klopp will have to spend within his means if he is to build on his Dortmund success.
He added: "To have no debt is our goal. We strive for maximum sporting success, but we do not spend more money than we are taking in."
Dortmund travel to Bayern Munich on Wednesday in the quarter-finals of the DFB Pokal.