The Borussia Dortmund coach has likened the Champions League matchday six clash to the Wembley showdown they had with Bayern Munich in May
Klopp's men are second on nine points in Group F following a 3-1 victory over Napoli in the last round of action, and know a win in the south of France will secure their place in the last 16.
"We qualified for this final-of-sorts 14 days ago against Napoli - it was very difficult to beat the Italian team, who only needed a draw to qualify, which would have been hard for any team in the world. But we got it right," he told reporters.
"We were proud that we did it. [Reaching the last 16] is a great opportunity that looked out of sight after the defeat against Arsenal, but now we have the chance to qualify to reach the next round. This is a very difficult group and getting out of it would make us very happy. We are very positive going into this game."
Dortmund's injury problems have yet to subside and will be without several key players for Wednesday's encounter against the Ligue 1 outfit, who are currently without a coach and already eliminated from the competition.
Klopp has revealed he will not risk playing Nuri Sahin if he is not fit, while defenders Mats Hummels, Neven Subotic and Marcel Schmelzer and midfielders Ilkay Gundogan and Sven Bender have been ruled out.
The coach said of Sahin's setback: "The injury is not a problem, the problem is the time. We will look at it in training, but we will not risk anything tomorrow, but if he does play, it would be good..."