The first-leg play-off between the Black Stars and the Pharaohs will take place at the Baba Yara Stadium in Kumasi on October 13
The tie will take place on Sunday, October 13, 2013 at 16:00GMT.
Ghana have been paired with Egypt in the final round of qualifying games to decide who makes it to the World Cup in Brazil.
The second leg could take place on the weekend of 15-19 November this year.
Two-leg ties will be played between both nations with the aggregate winner going to the finals in Brazil.