The 37-year-old will be joined by fellow Englishmen Stephen Child and Simon Beck who will be his assistant referees.
Clattenburg has taken charge of two other Olympic matches during these games, including Mexico's 4-2 victory over Senegal in the quarter-finals.
David Elleray, Chairman of the Football Association Referees' Committee is delighted with the appointment and thinks the English refereeing team should be considered as another gold for Team GB.
Speaking to the FA's official website, Elleray said: "The appointment of Mark Clattenburg to referee the Olympic Final with his English assistants Steve Child and Simon Beck is wonderful news and is in keeping with the outstanding achievements of so many people from Great Britain in these Olympics.
|GOING FOR GOLD
|6/1||Brazil are 6/1 to beat Mexico 1-0 in the Olympic final with Paddy Power|
"Match officials in all sports make an important contribution to the success of sport and the appointment of the English referee team to the final match should be seen as another 'gold' for Team GB.
"This appointment means that English officials have controlled the World Cup Final, Champions League Final and Olympic Final in the space of two years - a remarkable achievement which reflects well on the health of refereeing in this country.
"As with Howard Webb's World Cup Final appointment, this will be an inspiration to our young referees and will mean that the 2012 Olympics will have a lasting legacy in refereeing."