The strike was the 29-year-old’s fifth goal in only his sixth appearance in the colours of Les Canaris.
Nakoulma netted braces against Montpellier and Angers to keep his impressive form since arriving as a free agent in January and added another to his tally with a fine finish on Sunday.
After being played through by Alexander Kacaniklic in the 15th minute, the powerful forward whipped a low shot across the face of goal into the far corner from an acute angle to open the scoring.
However, Nantes could not hold on to the lead as they allowed Benjamin Corgnet to head home the equalizer from Cheikh Mbengue's cross in the 70th minute.
Nakoulma is now only four goals shy of eclipsing his career-best tally of nine league goals in club football, achieved with Gornik Zabrze in the 2011/201 and 2013/2014 seasons despite only playing a handful of appearances since moving to France.
Sunday's stalemate dealt ASSE a major blow for their ambition to compete in Europe next season. After fourth-placed Olympique Lyonnais lost and Olympique Marseille failed to win earlier in the day, Saint-Etienne had a chance to close in on their rivals but remain in seventh on 45 points, three behind OM having played a game less.