Tottenham welcome Real Madrid to Wembley on Wednesday with both teams looking to take a step closer to the knock-out stage of the Champions League.
The sides are locked level on seven points each after the first three games and they could not be separated when they met at the Bernabeu in October, with the game finishing 1-1.
Both teams come into the game licking their wounds following weekend defeats, but the spotlight is firmly on Zinedine Zidane's men, who have been floundering this season.
|Game||Tottenham vs Real Madrid|
|Date||Wednesday, November 1|
|Time||19:45 GMT / 15:45 ET|
TV CHANNEL & LIVE STREAM
In the UK, viewers will be able to watch the game live on television on BT Sport 2 or stream live online using the BT Sport app.
|UK TV channel||Online stream|
|BT Sport 2||BT Sport app|
The game will be broadcast live on television in the US on FS1 or the Spanish language channel ESPN Deportes. Viewers can also stream the game live online using Fox Sports GO or WatchESPN.
|US TV channel||Online stream|
|FS1 / ESPN Deportes||Fox Sports GO / WatchESPN|
SQUADS & TEAM NEWS
|Goalkeepers||Lloris, Vorm, Gazzaniga, Whiteman|
|Defenders||Trippier, Rose, Alderweireld, Vertonghen, Sanchez, Foyth, Aurier, Davies, Walker-Peters|
|Midfielders||Wanyama, N'Koudou, Dier, Sissoko, Dembele, Alli, Eriksen, Winks, Amos, Georgiou, Oakley-Boothe|
|Forwards||Son, Kane, Llorente|
Dele Alli is available for the first time in the Champions League this season after the England international served a three-match ban, while Ben Davies, who missed the corresponding fixture in Madrid, is also fit to take part.
Spurs have also been handed a boost with the news that Harry Kane is fit to play after the striker missed the weekend's Premier League defeat to Manchester United with a hamstring strain, but Victor Wanyama remains out of contention.
Potential Tottenham starting XI: Lloris; Davies, Alderweireld, Vertonghen, Sanchez; Sissoko, Dier, Alli, Eriksen, Son; Kane.
|Position||Real Madrid players|
|Defenders||Vallejo, Ramos, Nacho, Marcelo, Theo, Achraf|
|Midfielders||Kroos, Modric, Casemiro, Llorente, Asensio, Isco, Ceballos|
|Forwards||Ronaldo, Benzema, Vasquez, Mayoral|
Real Madrid have taken a 19-man squad to London for the game and they will be without a number of key players. Gareth Bale will miss out on a reunion with his old club, while Raphael Varane is also ruled out.
Goalkeeper Keylor Navas is injured, meaning Kiko Casilla will continue as number one, but there is good news after Isco was deemed fit enough to make the journey.
Potential Real Madrid starting XI: Casilla; Achraf, Ramos, Nacho, Marcelo; Casemiro, Kroos, Modric, Asensio; Ronaldo, Benzema.
BETTING & MATCH ODDS
At 6/5, Real Madrid are favourites to win according to dabblebet, with Tottenham priced at 11/5 to beat the reigning champions. A draw between the teams is considered a 5/2 bet.
Harry Kane and Cristiano Ronaldo are locked level on five goals each from the opening three games, but the Real man is favourite to score first at 5/2, with Kane close behind at 10/3.
Real Madrid's shock La Liga defeat to Girona at the weekend was a serious blow to the champions in the race for the title as it allowed Barcelona to move eight points clear and it has raised questions over Zidane's stewardship of the club this season.
The French coach will be desperate to put that embarrassing loss behind him by picking up a win over Spurs in London, but that will require his key players to step up a level, particularly considering that Mauricio Pochettino's men were left bruised by their defeat to Man United at the weekend.
Cristiano Ronaldo is the joint-top scorer in the Champions League this season, along with Harry Kane, but the Portuguese has been finding it difficult on the domestic stage, scoring just once in six league appearances so far.
If Real are to overcome a hungry Spurs outfit at Wembley, they will need the likes of Ronaldo to hit the ground running and, while the season is far from over, the consequences could be far-reaching for Zidane should they fail to win.