Tottenham turned in one of their finest performances of the season on Thursday, defeating Leicester City 6-1 thanks to an inspired display from Harry Kane, who scored four goals to move top of the Premier League Golden Boot race.
That race is all that could be decided on Sunday in this game, however, with Spurs facing an already-relegated Hull safe in the knowledge that they will definitely finish second.
Both Kyle Walker and Kieran Trippier missed the victory over Leicester, with Moussa Sissoko playing as a wing-back.
Trippier could return against Hull, having only missed out through a concussion, but Walker is expected to miss the encounter.
Elsewhere, Danny Rose is out for the rest of the season, along with Harry Winks and Erik Lamela.
Spurs have no players suspended for the encounter with Hull.
POTENTIAL TOTTENHAM LINE-UP
Spurs opted to select Moussa Sissoko at right wing-back, against Leicester and ended the game 6-1 winners.
If Kieran Trippier is fit, however, then the former Burnley defender is likely to be restored to the starting XI.
Mousa Dembele played through the pain barrier on Thursday, and Dele Alli could be restored to central midfield to allow the Belgian a rest, with Son Heung-Min deployed further forward after scoring twice against Leicester.
HULL TEAM NEWS
Already relegated Hull have a series of injury worries, including that of key central defender Harry Maguire, who could miss the game with a knee injury.
Maguire has impressed thus far this season, despite Hull's problems, and has been heavily linked with a summer exit to a bigger club, with Spurs reportedly interested.
Abel Hernandez and Lazar Markovic are both out with knee problems, while David Meyler, Ryan Mason and Will Keane are all on the long-term injury list, along with Moses Odubajo.
BEST OPTA MATCH FACTS
Since winning in their first ever Premier League encounter, Hull are without a win in their last eight games against Tottenham (D2 L6).
Spurs have only conceded two goals in their last six Premier League games against Hull, keeping clean sheets in each of their last two.
Harry Kane has scored four hat-tricks for Tottenham this season, including three in the Premier League. The only player to score more than three hat-tricks in a single Premier League season was Alan Shearer (5) in 1995-96.
TV COVERAGE & KICK-OFF TIME
The game is due to kick off at 15:00 on Sunday and will not be televised live in the UK. Highlights will air at 22:30 on BBC One.