Sunday night saw Real Madrid record an impressive 3-1 victory away to Real Sociedad, inflicting a first defeat of the season on the Basques and successfully coming through their biggest challenge of the campaign so far.
Los Blancos were without a number of players for the visit to San Sebastian, yet Wednesday night's game against Betis will see the return of Cristiano Ronaldo and Marcelo from suspension, while Toni Kroos is also likely to be fit for selection.
Boosted therefore by the availibilty of some of the most influential members of the squad, the Spanish champions are clear favourites to claim three points against a Real Betis side who have not won at the Bernabeu since 1998; bet365, who are live streaming the game for UK-based customers, price a home win at 1/8 (1.12) while Betis are available at 16/1 (17.00) and the draw can be backed at 9/1 (10.00).
While Real Madrid are big favourites, history tells us that we should expect goals at both ends with Betis regularly finding the back of the net on their trips to the Spanish capital.
Both teams to score has paid out in five of the last six matches between Madrid and Betis at the Bernabeu, and the price of 7/10 (1.70) for a repeat could generate some interest.
For a slightly higher price, backing both teams to score and over 2.5 goals at 4/5 (1.80) looks like a solid selection, especially considering Real Madrid's defensive record at home - Zinedine Zidane's men have conceded in 11 of their last 15 home league games, including in each of the last six, while Betis have netted in ten of their last 12 encounters on the road.
Los Blancos, however, can set a new world record of 74 consecutive games scoring if they find the back of the net on Wednesday evening and their strength in front of goal should give punters plenty of confidence in backing a high scoring encounter.