Though there are six capital clubs in the top flight, only three realistically harbour hopes of finishing as London's top club.
As reigning champions Chelsea will be aiming to consolidate their status as the capital's best team, and Antonio Conte's men are understandably the favourites with Genting to end the season above their geographical rivals. The Blues can be backed at 17/20 (1.85) and last season they finished seven points above second placed Tottenham.
Spurs, for their part, are second favourites in the market at 12/5 (3.40) and the last two season have seen the north Londoners push for the title before falling just short.
The previous term, however, they did manage to achieve something historic, finishing above their eternal rivals Arsenal for the first time in 22 years. The 2015-16 season saw the Gunners pip Spurs to the title of top London club on the final day of the season as Arsene Wenger's men claimed second place behind surprise champions Leicester.
Last season's fifh-placed finish, however, was not good enough for the red half of north London and they will be expected to not only secure Champions League football but also re-establish their dominance over Spurs.
Wenger's men are offered at 14/5 (3.80) to finish as the top London club and the Gunners are historically the most successful side in the city with 13 league titles.
To the east, West Ham are quietly confident of improving on their showing in the previous campaign where Slaven Bilic's men finished in the bottom half of the table. Fans will hope that that a number of seemingly shrewd signings will elevate the Hammers to the upper echelons of the division, although even the most optimistic of supporter cannot believe that West Ham will finish as top London club.