Relegated Western Stima will face a formidable side Ushuru as they begin proper life at National Super League.
Western Stima, who dropped down from the top tier last season, will host Ushuru , who narrowly missed out on a promotion last season, in what promises to be the match of the weekend in the lower tier.
Both teams are going into the second round of matches with confidence having won their opening matches by an identical 2-0 scoreline last weekend.
Meanwhile, Muhoroni Youth will kick-off their NSL campaign with a home tie against Kenya Police at the Muhoroni Grounds.
Muhoroni, who were relegated from the top tier alongside Stima, skipped their opening match against KCB.
They will face a gritty Police side, who finished sixth in the 2017 edition and are looking for comeback, having dropped two points in a stalemate against FC Talanta in the opening match.
In other matches, Green Commandos will entertain Nairobi Stima as Coast Stima welcome Kisumu All-Stars at the Mbaraki Sports Club in a double header that will also see Modern Coast Rangers face KCB.
Kangemi AllStars take on Nakuru AllStars as GFE 105 hosts St Joseph Youth. Bidco United will be at home to Kibera Black Stars at Thika sub-County Stadium.
Administration Police will be up against Isibania as FC Talanta host Nairobi City Stars in one of the two matches set to be beamed live on Bamba Sport .