Not many sides manage to win at Juventus' Allianz Stadium and Spurs know that scoring an away goal on Tuesday could hold the key to them progressing.
Mauricio Pochettino's side have scored in each of their last 20 matches in all competitions and also netted in each of their Champions League group stage matches.
All eyes on number nines
Both sides boast a classic centre-forward, with Gonzalo Higuain and Harry Kane likely to lead the line in impressive fashion.
Higuain has not been quite as prolific this season as in previous campaigns with the Argentine sharing goalscoring responsibilities with Paulo Dybala, but his countryman will be missing on Tuesday night however.
The former Real Madrid man has been firing in recent weeks and six goals in his last four games show he will certainly be a threat.
Kane, meanwhile, has been in sensational form with eight goals in his last eight matches and six strikes so far in this season's Champions League.
Llorente to haunt Juve?
Clearly the two strikers will pose the biggest threat in the final third, but there are plenty of other names to consider in the goalscorers market.
Juve's Mario Mandzukic, who scored an overhead kick in the 2017 final, is also offered at 13/5 (3.60) to bag anytime.
From midfield, Christian Eriksen can be backed at 11/2 (6.50) to score his second European goal of the season, whilst Mirlaem Pjanic, who is also looking for his second Champions League goal this term, is the same price.
Prices correct at time of writing. Please gamble responsibly.