Inter have confirmed midfielder Ever Banega will miss Sunday's Serie A game against Empoli on Sunday due to a twisted knee.
No timescale has been set for Banega's recovery, with the Argentina international having endured a mixed season since signing from Sevilla.
Inter coach Stefano Pioli will also be without star striker Mauro Icardi as the captain is suspended for kicking a ball at an official during last weekend's 1-0 defeat to Juventus.
Pioli has named teenage striker Andrea Pinamonti in his 21-man squad, with Ivan Perisic banned and Marcelo Brozovic unavailable due to a broken toe.
Gabigol is in line for his Inter start in place of Icardi.