Lagging behind Real Madrid in the Spanish title race, Barcelona will be aiming to get one over on their historic rivals be reclaiming the Champions League trophy.
Having seen Los Blancos secure a record 11th title last season, Luis Enrique’s men are available at 10/3 (4.33) with bet365 to bring the silverware back to Catalonia for the sixth time.
While the Blaugrana must find their way past Paris Saint-Germain 33/1 (34.00), Zinedine Zidane’s men are priced at 9/2 (5.50) as they prepare to take on Napoli 66/1 (67.00) in their last-16 tie.
Meanwhile, Bayern Munich look like the most likely candidate to bring a halt to Spain’s recent dominance in this competition, with Carlo Ancelotti on offer at 4/1 (5.00) to become the most successful manager in European Cup history by adding a fourth winners medal to his collection.
However, the Germans are faced with a difficult knockout round tie against Arsenal, who are priced at 25/1 (26.00) to finally win their first ever Champions League title.
In contrast, Atletico Madrid have been handed a relatively straightforward tie against a Bayer Leverkusen 150/1 (151.00) team enduring a difficult Bundesliga campaign, making their 10/1 (11.00) price seem rather generous.
While their own domestic form has been relatively disappointing, that price could prove a savvy investment on a team that has reached two of the last three finals under Diego Simeone.
Beaten by Barcelona in the 2015 final, Juventus are available at 11/1 (12.00) to finally translate their domestic dominance to the continental stage with a first title since 1996, having been drawn against Porto 125/1 (126.00) in the last-16.
Also taking on Portuguese opposition in Benfica 150/1 (151.00), Borussia Dormund are a 12/1 (13.00) shot to add to their solitary European title this season.
That same 12/1 (13.00) price probably appears more generous on Pep Guardiola’s Manchester City, even with an impressive Monaco 66/1 (67.00) team awaiting them in the first knockout clash.
Having shocked English football by lifting the Premier League title last season, Leicester City are sure to attract some attention at 66/1 (67.00) to overcome their domestic struggles by getting past Sevilla 33/1 (34.00) and causing an even greater upset in the Champions League.