Arsenal have won their last 12 home Premier League matches in a row but number 13 will certainly take some doing.
Manchester United and Jose Mourinho are in town on Saturday as the Portuguese faces his arch rival Arsene Wenger in a crunch league clash at Emirates Stadium.
"Man Utd are a dangerous team, they have made fantastic results so to beat a team like that you need to be at your best and that’s what I want to focus on," said Wenger ahead of the game.
A recent turn of fortunes has seen Arsenal record impressive victories over Tottenham, Burnley and most recently Huddersfield who the Gunners scored five past.
The Gunners haven't won three successive home league games against United since May 1991 but will be confident of getting a positive result on Saturday after their recent run of form.
Alexandre Lacazette will miss Saturday's match with a groin injury sustained during the 5-0 thrashing of Huddersfield.
Chile star Alexis Sanchez had a hamstring problem against Huddersfield Town but should be fit for the weekend.
"Look, we have offensive weapons, you know. We have Welbeck, we have Giroud, we have Wilshere who all came on," said Wenger.
"They are all offensive players. I will see what I do for Saturday but ideally you wanted him [Lacazette] there."
Spanish midfield maestro Santi Cazorla remains a long-term absentee with an Achilles injury and recently suffered another setback in his recovery which saw him undergo surgery for ninth time.
Arsenal have no players suspended for this game.
ARSENAL POTENTIAL STARTING LINE-UP
Wenger is likely to field Alexis up front in place of the injured Lacazette while he faces a choice between Alex Iwobi and Danny Welbeck in the front three, although the latter remains more likely to start against his former club with Mesut Ozil starting in the No.10 role.
Hector Bellerin and Sead Kolasinac will start in the wing back slots and the back three of Shkodran Mustafi, Laurent Koscielny and Nacho Monreal will remain unchanged.
MAN UTD TEAM NEWS
Mourinho is likely to deploy a three-man defence for the game on Saturday while Zlatan Ibrahimovic could make his first start since injury.
Romelu Lukaku has scored just once in his last 11 games in all competitions and may find himself starting on the bench for the first time this season.
United won their last league match against Watford on Tuesday and have three successive league wins to their name going into Saturday's match
Lukaku is the club's top goalscorer this season having scored 11 goals.
BEST OPTA MATCH FACTS
Arsenal have lost just one of their last five Premier League home games against Manchester United (W2 D2), winning each of the last two without conceding a goal.
The Gunners have not won three successive home league games against the Manchester United since May 1991.
No side has won more Premier League away games at Arsenal than Manchester United (7, level with Liverpool), while only Chelsea (4) have won more at the Emirates than the Red Devils (3).
This will be the 18 th meeting between Arsene Wenger and Jose Mourinho, with the Portuguese manager losing just two of these (W8 D7 L2). However, those two losses have come over the last four meetings (W1 D1 L2)..
Mesut Özil has been directly involved in four goals in his last four Premier League appearances against Manchester United (two goals, two assists).
Mesut Ozil has assisted Olivier Giroud 14 times in the Premier League – only two players have assisted another more often for Arsenal in the competition (Robert Pires to Thierry Henry, 17 and Thierry Henry to Freddie Ljungberg, 15).
Olivier Giroud has scored 16 goals as a substitute in the Premier League, the fourth highest tally in the competition (Jermain Defoe 23, Ole Gunnar Solskjaer and Kanu 17).
TV COVERAGE & KICK-OFF TIME
The match is being televised on BT Sport in the UK while NBC will carry the match in the United States, with kickoff at 19:45 GMT.