Team GB manager Stuart Pearce has recalled Daniel Sturridge and brought in Scott Sinclair for the Olympic hosts' clash with uruguay, with Ryan Giggs dropping to the bench.
Fellow Welshman Craig Bellamy will take the captain's armband after two excellent performances so far at the games.
Ryan Bertrand also comes into defence in place of James Tomkins, with Micah Richards moving back into central defence and Neil Taylor moving to right-back.
La Celeste include Luis Suarez and Edinson Cavani up front but make two changes with Matias Aguirregaray replacing Emiliano Albin at the back and Tabare Viduez replacing Maximiliano Caldaza in midfield.
Team GB: Butland; Taylor, Richards, Caulker, Bertrand; Ramsey, Allen, Cleverley; Bellamy (c), Sturridge, Sinclair.
Uruguay: Campana; Arias, Coates, Rolin, Aguirregaray; Ramirez, Rodriguez, Viudez, Arevalo; Cavani, Suarez (c).