The showdown at White Hart Lane between the two rivals dominates the Twittersphere, with plenty of Andre Villas-Boas' squad quick to display their delight at the result
While Sunday's big game clearly dominates the thoughts of those involved during the game, elsewhere we have Joey Barton backing QPR to stay up, Nile Ranger taking his former club Newcasle to task over his exit and Neil Lennon preparing for another spanking against Juventus.
It's not all depressing news, though, as Gary Lineker gets confused with an amusing lookalike and Cristiano Ronaldo feels the love on his return to Old Trafford.
"YESTERDAY IN WHL WAS AMAZING!!!! Great atmosphere thanks. For ur support u was top class! So proud to b spurs. Player head up today LOL"
Tottenham full-back Benoit Assou-Ekotto sounds delighted with yesterday's big result. Thank you, Benoit, for the fantastic gold boots.
"Massive win today to take us back into 3rd the lane was rocking, roll on Thursday #buzzing #coys"
Winger Aaron Lennon, (pictured right celebrating with team-mate Scott Parker) scored one of his team's goals during their 2-1 win over Arsenal and he now believes a top four place is well within Tottenham's sights.
"Worth the 2 days in bed with sickness just for those precious 3 points today....back to bed so I'm 100% for Inter Milan Thursday #COYS"
Tottenham right-back Kyle Walker reveals that he was nursing an illness prior to the game.
"It wasn't a good day today. Important to keep focus and motivated for next match! #championsleague"
Gunners playmaker Santi Cazorla has already set his sights on Bayern Munich after the team's derby day misery.
"Perdu 2-1 contre les Spurs. Super déçu de perdre ce derby... Lost 2-1 against Spurs. Very disappointed to lose this derby.."
Arsenal striker Olivier Giroud is so disappointed he tweeted it in two different languages.
"MUTUAL CONSENT 3YEARS LEFT.... Every just have a big think about it ☺"
Former Newcastle striker Nile Ranger doesn't hold back with his honest assessment of his departure from the club.
"Happy QPR won at the weekend. Gives them a chance that. Even with some of the negativity directed at me, I hope you stay up."
Marseille midfielder and man of the world Joey Barton (pictured left) is backing his parent club QPR to still beat the drop after they beat Southampton 2-1 at the weekend.
"Another great week to look forward to..starting with the semi final draw..then off to Turin..lookin forward to seeing our fans out there"
Celtic manager Neil Lennon focuses himself on the challenges ahead this week, starting with Juventus in Italy.
"I'm looking forward to return to Old Trafford. I've so many good memories there. It will be an exciting game and our goal is to win."
Real Madrid forward Cristiano Ronaldo sounds delighted be back at his former club Manchester United, albeit for just the one game. For now.
"At the airport and just got mistaken for @GNev2 . Knew I should have shaved this morning."
Is it a bird? Is it a plane? No, it's Match of the Day presenter Gary Lineker. At least it wasn't Luke Chadwick.