The 76-year-old head of state will not be attending the clash against Paraguay and has expressed his hope that the best team comes out on top
The 76-year-old says he does not want to be seen gloating in his neighbouring nation should Uruguay emerge victorious from the match.
Oscar Tabarez's men disposed of Peru in the semi-final to book their place in the showpiece with Paraguay but the politician will not be one of the 58,000 inside the stadium watching one team lift the trophy.
"I do not want to be boastful if Uruguay win," he told radio station Monumental.
"I have to be diplomatic. We had good luck to pull off the win against Argentina. They are a good neighbour."
After joking that he hopes the Argentinians will give Uruguay "more good results" in the future, he gave his hopes for the game itself, adding: "May the gods, if any, enlighten who is better in the final of the Copa America between the football teams of Uruguay and Paraguay."
Uruguay are expected to to pick up the trophy after disposing of pre-tournament favourites Argentina in a penalty shoot-out at the quarter-final stage.