The Manchester City goalkeeper, established as first choice for his country, missed his club's 3-2 Community Shield win with a back problem, though his manager, Roberto Mancini, noted that it was "not serious", while the Chelsea forward suffered a toe problem during his substitute role at Villa Park.
Three Lions boss Roy Hodgson has not called up a replacement for either man, so Norwich City's John Ruddy will battle it out with Team GB's Olympic No.1, Jack Butland, to play in goal in Berne.
|ONE STEP BACK?|
|10/1||England are 10/1 with William Hill to lose 2-1 to Italy in Berne|
Andy Carroll, Jermain Defoe and Theo Walcott are the remaining strikers available for the friendly.
The clash on neutral ground is a repeat of the quarter-final in Poland and Ukraine, in which Cesare Prandelli's men knocked the Three Lions out on penalties on their way to the final.