The Black Stars and will seek to entertain their fans in London against the South Americans, after a cancelled friendly with Nigeria this month due to civil unrest
The 2014 World Cup hosts will square off with the 2010 World Cup quarter-finalists at Fulham's Cravern Cottage on September 5.
The Samba Boys were supposed to play Egypt on September 6, but the encounter was called off with The Pharaohs aiming to focus on the African Cup of Nations qualifiers a few days earlier.
The Brazil fixture occurs three days after the four-time African champions host Swaziland in a 2012 Afcon qualifier in their capital, Accra.
Brazil won their last friendly against Ghana 1-0 at the Rasunda stadium in Stockholm, Sweden in 2007. Prior to that the South Americans handed the Black Stars a humiliating 3-0 defeat at the last 16 stage of the 2006 World Cup in Germany.
Tickets are available from www.fulhamfc.com/tickets or via 0843 208 1234. Tickets start from just £25 (£15 for under 16s).