There had been speculation that MLS was hoping to join the tournament organised by Conmebol but Garber insists they need to focus on improving their status in the Concacaf before they can start thinking about the Copa Libertadores.
"There's always this buzz about Copa Lib every now and again as if we're engaged in conversations with Conmebol about it, and we're not at all," Garber told reporters.
Liga MX side Monterrey captured their third straight Concacaf Champions League title on Wednesday in a riveting second leg of the final against Santos Laguna, and it marked the fourth time in five years -- the time in which the tournament has been in its current format -- that the final was an all-Mexican affair.
Only MLS side Real Salt Lake came close to winning the crown, when it pushed Monterrey to the brink before succumbing at home in the second leg in 2011. Seattle and Los Angeles fell in the semi-finals this year.
"We are very focused on our confederation's tournament, the Concacaf Champions League, and we've got to get into the finals and win it, and we have not been able to do that in its most recent iteration," Garber said.
"I watched the Monterrey-Santos game, and it broke my heart that we didn't have a team in it. We've got to get more engaged with getting better in our regional tournament.
"We have a goal of being one of the top leagues in the world, and we've got to start by being one of the top leagues in our region.
"Right now Mexico is doing a pretty good job of leading that front, so no conversations at all with Conmebol at this point."