The new signing from Benfica struck to give his side the perfect result ahead of their opening La Liga game next week
Valencia completed their pre-season preparations with a morale-boosting 2-1 win over AC Milan at the Mestalla.
Under new coach Nuno Espirito Santo, the hosts looked timid in the opening stages as Milan dictated possession, but they took a spectacular 18th-minute lead after settling into the game.
New signings Rodrigo, Nicolas Otamendi and Andre Gomes all started, but it was Paco Alcacer, a rising star under the previous regime, who broke the deadlock when he pounced on Cristian Zapata's poor square pass before lobbing debutant Diego Lopez from fully 40 yards.
Keisuke Honda drew Milan level 10 minutes later as his 30-yard free-kick flew in via the right-hand post, but the Liga side restored their lead seven minutes before the break when Rodrigo squeezed between a couple of defenders and fired into the bottom-right corner.
The second period lacked the same intensity and flow of the first half, with a host of substitutions from both sides disrupting the rhythm.
The game did begin to liven up once more in the final 25 minutes, but neither side could add to the scoring.
Valencia substitute Sofiane Feghouli - on for Alcacer - went close when he skewed a shot wide from 12 yards in the 68th minute, before, at the other end, Jeremy Menez narrowly missed the corner with a shot from the edge of the area.
The best chance of the second half fell to Michael Essien with 12 minutes left, but replacement goalkeeper Yoel turned his header away in acrobatic fashion as Valencia held on to a morale-boosting victory just six days before they start their La Liga campaign at Sevilla.