A young Arsenal side were gunned down by Dartford at Princes Park, with their only goal of the night coming from Sanchez Watt.
First-team coach Terry Burton was able to include some of the players who had been on the senior squad’s tour to Asia, with Ignasi Miquel, Craig Eastmond, Chuks Aneke and Thomas Eisfield some of the recognisable names in the starting lineup.
And, despite controlling possession for long stages, and much like the senior team, the visitors went behind against the run of play thanks to a goal from Dartford striker Harry Crawford.
Serge Gnabry came close to levelling the match for Arsenal, striking an effort off the post from the edge of the box just before the break, but the Gunners pegged back the hosts from the penalty spot thanks to Watt shortly after half-time.
But Burton's young side were defeated by a late goal from Ryan Hayes after a poor backpass from Sead Hajrovic let the Dartford man in to poke home a winning goal.
Newcastle's second string side ran out easy winners against neighbours Gateshead, with goals from Mehdi Abeid, new signing Romain Amalfitano, Conor Newton and Marcus Maddison, while Micky Cummins scored the only goal for the hosts.
The Magpies started quickly, with Abeid putting them a goal up after six minutes with an impressive strike. However, Amalfitano scored an even better goal almost 20 minutes later, running from inside the centre-circle before beating two defenders and scoring with a powerful finish.
The visitors then got one back five minutes later, when Cummins smashed home from 10 yards after the visitors failed to clear Glen Wilson's long throw.
Following a relatively quiet 25 minutes in the second half, Newcastle added to their lead in the 70th minute when Newton headed home from a corner, and barely a minute later they added a fourth as substitute Maddison lobbed Gateshead keeper Adam Bartlett.
It was a tale of penalties in Everton's game against Tranmere, with both sides missing one, but the Rovers converting their second opportunity of the night from the spot to win the Liverpool Senior Cup.
The Toffees named a strong side for the game against their near-neighbours, with Seamus Coleman making an appearance, as well as Jack Rodwell and Apostolos Velios up front alongside Ross Barkley.
After just over 10 minutes the Premier League side took the lead, with Velios volleying home from a corner in a crowded penalty area, and it stayed that way until half-time.
Just after the break Everton keeper Jan Mucha made a fine save to keep out a spot kick from Andy Robinson but, just 20 minutes later, he was called into action again. The hosts were awarded yet another spot kick and this time captain James Wallace made no mistake as he fired the ball home low into the corner.
With almost 10 minutes to go, Conor McAleny was awarded a penalty for Everton after being tripped in the area and, after picking himself up to take the kick, he saw his effort saved by newly-signed keeper Jason Mooney.
As the match entered injury time, Rodwell's loose pass was intercepted, with Robinson on hand to atone for his missed spot kick and convert to win the cup for Rovers.