The organisation will look into reported abuse towards Czech Republic’s Theodor Gebre Selassie and Italy’s Mario Balotelli during their respective games
Czech full-back Theodor Gebre Selassie claimed he had "noticed" some racist chanting aimed towards him during their 4-1 loss against Russia.
Italy forward Mario Balotelli, meanwhile, was reportedly the subject of racist abuse during his side's 1-1 draw against the current European and world champions.
Neither national team made an official complaint to Uefa, but European football's governing body has confirmed new information has made an official investigation viable.
A statement released by the organisation read: "Following the provision of new independent information [Tuesday], regarding the two cases of alleged racist chanting in the Spain-Italy and Russia-Czech Republic matches, Uefa is now conducting further investigations.
"There are, however, no disciplinary proceedings opened at this moment in time."