The Dortmund-bound attacker scored 21 goals and provided 12 assists for the Foals last season, and is now ready to make his mark on the international level, the trainer believes.
According to Low, Reus is an option not only as a winger and supporting striker, but as the focal point of his 4-2-3-1 formation.
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"Marco Reus has had a great development. He's still trying to prove himself in the national team," Low told reporters on Wednesday.
"As a player, he can be used in different positions. I would like to see him up front, that we can test in training. He's never played there before, but for me it's a possibility."
Other options in the position of central striker include Miroslav Klose, Mario Gomez and Cacau. Regarding Klose, who missed several weeks for Lazio recently, the trainer's assessment was not quite positive.
"He is not in top form, he was hurt for a long time," Low said.
When asked about comparisons between his playing style and that of Dortmund, the trainer admitted similarities between the two but rejected the notion that he took notes from Jurgen Klopp.
"We've developed our ideas over many years, we don't take them from elsewhere. But the way we play is not unlike that of Dortmund."
Germany are currently at a training camp in Sardinia, preparing for Euro 2012.