Coach says exclusion is follows three-match suspension for Roma for elbowing opponent, and warns players they will have to play regularly for clubs to make international cut
The Roma midfielder was not called up for the encounters after he was suspended for three games towards the end of the Serie A season.
The exclusion is his second this year after being dropped against Slovenia as Prandelli sticks to his strict code of conduct which states players who are ill-disciplined for their clubs will not be called to the national team.
"It was not down to a technical choice, but because of his behaviour with Roma," Prandelli told the press on Monday.
"Daniele must find some serenity and for him the doors to la Nazionale will always be open."
Prandelli also warned players he would not be calling anyone who does not play regularly for their club, including AC Milan's Antonio Cassano.
"From then [September] onwards those who want to be picked for the team will have to play for their clubs. It's not just about consistency, but those who don't play lose motivation," he added.
"Cassano? This is valid for him also. He will have to play more for Milan."
Meanwhile, Thiago Motta has been forced to leave the Coverciano camp with a muscular injury he sustained in the Coppa Italia win over Palermo.
Italy are in total control of their Euro 2012 qualifying group with a five-point lead over their nearest rivals, and a game in hand.
A win against Estonia on June 3 would leave them needing only two more victories from their final four games to ensure top spot in Group C and a place in Poland and Ukraine next year.