The Spain defender urges Real Madrid to look to the future under Carlo Ancelotti, adding that the players are already noticing a difference in approach at the club
Los Blancos endured a turbulent final season under the Portuguese, characterised by an absence of trophies and strained relations between the coach and his players.
However, speaking to journalists after his side's 2-1 win over Everton in the semi-finals of the Guinness International Champions Cup, Ramos stressed that the Liga giants now have a glorious chance to make a fresh start under their new trainer.
"We have to forget Mou [Mourinho] and focus on what we want to instill with Ancelotti," the 27-year-old told reporters.
"This system is not new to us, but want to try out the best role for each player."
Ramos says Ancelotti has already brought a different philosophy to the team, and believes the current Madrid squad is more than capable of adapting.
He added: "We have great players with great quality and we must adapt to the system. We have players that make a difference, spilling forward easily. A great squad.
"It's always good to bring players [on tour] who know the club and know what it means to wear this crest. Whoever does not know becomes a quick learner. You have to know how to take your opportunities because the train passes almost instantly here."
Cristiano Ronaldo and Mesut Ozil both scored in a victory over Everton on Saturday, but it was the presence of Iker Casillas that especially pleased Ramos, given the captain had been ostracised during the final six month's of Mourinho's tenure.
"It was very good, for me it to see him behind us in defence," the former Sevilla man said.
"To us remains the best goalkeeper in the world and, in that sense, has our confidence. There are players who are pushing hard and Diego Lopez has to take credit for last season."
Madrid will play Chelsea or AC Milan in the International Champions Cup final this week.