The midfield star believes changes are vital to help the club continue to compete for titles and take their "revenge" in the Champions League following their 7-0 loss to Bayern
The Blaugrana stormed to the Liga title with a record-equalling points tally of 100, but a 7-0 aggregate semi-final defeat to Bayern Munich in the Champions League left many to consider the Catalans' era of dominance in Europe to be drawing to a close.
Tito Vilanova has responded to Barca's shortcomings with the €57 million (£48.4m) signing of Brazil starlet Neymar, and Iniesta admits that further changes are vital if the club is to mount a serious challenge in Europe and take "revenge" in the competition.
"There will be changes, because it is the evolution that has to happen every year in order for the club to continue competing at the highest level," he said in an interview on Cuatro.
"Next year, we will not reach the semi-finals of the Champions League with practically no competition. We will try to take our revenge in this competition."
Iniesta notched an impressive 16 assists in 31 appearances in Barcelona's title-winning Liga campaign last season, but the 29-year-old insists personal tallies are not the correct way to judge the success of a season.
"I feel content at having finished a season and I have the feeling things have gone well, more or less," he contined. "You can't analyse it by the goals you've scored or the assists you've been able to create, because there are many more crucial things in the game that mean more than how many goals or passes.
"My goal is simply to finish the year and think I have done better than in the last one."