The centre-back feels that the reigning champions can still claw their way back into contention, and was pleased with his side's display against Levante
The reigning champions are trailing Barca by 11 points following their loss against Betis at the weekend, but Pique believes that they can still trouble the Blaugrana this term.
"We’re having a great start to the season and that’s allowed us to claim the top spot in the league," he told reporters following the game.
"The difference with Madrid is certainly not definitive, though. You can never count Real Madrid out."
The centre-back then went on to praise the Catalan club's defensive performance in their 4-0 win over Levante after they looked vulnerable at the back earlier this campaign.
"We’ve been conceding a lot of goals recently from isolated plays, but today we put in a good defensive performance."
Tito Vilanova's side currently hold a three-point lead over second-placed Atletico Madrid.