The attacking midfielder has responded to the centre-back's criticism, saying that the Blancos defender has overstepped the mark with his appraisal of the Blaugrana
The Portugal international labelled Iniesta and his team-mates 'theatrical' after the attacking midfielder called for a penalty in the high-profile encounter, and the Spaniard is not amused with Pepe's comments.
"Of course I am affected by what he said. Every person is entitled to have an opinion and say that a certain action was a penalty. However, it cannot go any further than that. There are boundaries," Iniesta told Onda Cero.
"If a player speaks about you and your team-mates like this, you feel offended.
"I'm not theatrical in any way, and neither are the other guys. These comments hurt because they are a personal attack."
Barcelona currently sit first in La Liga, holding an eight-point lead over Real Madrid.