Los Blancos, who currently have 97 points, have already clinched the Spanish league title, and now have a chance to make history by becoming the first team to reach the century milestone in a season.
"We want to make history by taking 100 points and we also want to finish the season celebrating the title at the stadium," Ramos told Real Madrid's official website.
"That's our goal because it is an impressive number and it will always make people remember this edition of La Liga. With a bit of luck, hard work and consistency we could take three points to finish the season with a bang before our fans."
"I have total faith in my teammates and the team," he said. "I think scoring goals is as important as keeping a clean sheet and it would be great to concede no goals in our last game.
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"We want to score as many strikes as possible so people's minds are eased before the holidays after seeing their Real Madrid side win and celebrating the title."
Ramos then looked back at the team's performance throughout the season, and vowed to help the Los Blancos improve even further.
"It is unforgettable to celebrate in Cibeles, especially after the great efforts and sacrifices we made to win. You see all the supporters there, feeling proud of their team. It's always nice to see that. It makes Madridistas and all footballers proud to be at Cibeles.
"We want to continue working the way we do. We've been together for a while and we feel better each year. I hope this is the start of a great era at Real Madrid, to be remembered in the future as a time of many titles.
"I'm proud of my performances this season, but I'm prouder of the whole team and of how we've all improved and performed. The merit belongs to the entire squad, regardless of how much or little anyone has played."
Since March, Goal.com has been publishing exclusive extracts from Luca Caioli's new book, Ronaldo: The Obsession for Perfection. Friday's excerpt looked at the mutual appreciation between Cristiano and Jose Mourinho after the two Portuguese led Real Madrid to La Liga glory earlier this week. Don't miss it!