The Spain goalkeeper is targeting silverware on two fronts this season and is eager for "revenge" against Juventus in the final of Europe's secondary competition
The Spaniard moved to the San Paolo from Liverpool on loan last summer and though the Partenopei's title challenge has faltered of late, he insists he can end the campaign with silverware - and is desperate for "revenge" against Juventus in the Europa League final in Turin.
"For me, there is no difference between the Coppa Italia and the Europa League," he told La Gazzetta dello Sport.
"I have no preference – I just want to win them both. Even more so now that we have quite a good advantage in the League table in terms of the top four.
"European nights are always special. Juve in the final? That would be a nice bit of revenge for us.
"We believe in second place [in Serie A]. We will fight until the end because it's an important goal for this club."
This is Reina's first spell in Italian football after a lengthy career in La Liga and the Premier League and the Spain international believes the game is more complex in Serie A.
"Compared to Spain and England, it is true that the Italian games lack a bit of speed. But it is definitely more tactical," said the former Barcelona man.
"It is not true that it's a defensive game, but, it must be said that when you have the points in the bag, you start to move back."