The current Heerenveen boss feels the Rossoneri are taking a major gamble by appointing the former midfielder as Massmiliano Allegri's successor
The San Siro side parted ways with Massimiliano Allegri on Monday due to the Italian outfit's disappointing performances in 2013-14 and Seedorf announced on Tuesday that he had called time on his playing career in order to take charge of the Rossoneri with immediate effect.
Nevertheless, Van Basten is not convinced that his fellow Dutchman is the right man for the job at this stage of his career.
"They have opted for Seedorf, which makes sense in some way, but is also a big risk," the former Milan striker told NOS.
"You never know how he will cope with the situation and solve things. It's not the wisest thing to do in my opinion, but I'm not the one making the decision."
Van Basten then went on to stress that there a number of aspects that speak in Seedorf's favour as well, before comparing his compatriot's situation to his own first steps into coaching as Netherlands boss in 2004.
"He is fluent in Italian and has enjoyed a long and successful career. Those are important things, too," he reasoned.
"The difference with my own situation is that he's going straight into coaching after hanging up his boots. I completely left the game after retiring and then had to make a comeback."
Van Basten wore the Milan jersey between 1987 and 1995, when he was forced to retire due to injury after two years on the sidelines.