The 36-year-old forward is gunning for all three points when Udinese take on the Bianconeri in Turin on Sunday
The Zebrette currently lie 11th in the table and their talismanic forward is eager to build on upon last weekend's 1-0 win over Fiorentina by stunning the league leaders in Turin.
"It's going to be a tough match against Juventus, but we are on the way back again," the 36-year-old attacker told Udinese Channel.
"We showed what we're made of against Fiorentina and Catania and we're going to Turin to give our all.
"We have to play our own game and have to approach them without fear. You never know what will happen in football, although fact remains that Juventus are a great team."
Di Natale – who has scored at least 23 goals in each of the last four Serie A seasons – has netted four times in 12 appearances in the current campaign.