The defender feels it is "imperative" that his side secure a win over Rafa Benitez's title challengers and has called for "ferocity" in their remaining Champions League matches
With both the champions and Rafa Benitez's side locked on 28 points from 11 games, just three points behind leaders Roma, Sunday's meeting in Turin is already being billed as a decisive encounter in the race for the Scudetto this season.
Bonucci is under no illusions as to the importance of a win for Antonio Conte's men, and is expecting a stern challenge from the Partenopei.
"It's imperative that we win in our beautiful stadium in front of our fantastic fans," Bonucci told Juve's official website.
"I'm expecting a real cup final between us and Napoli, it will be a great game. May the best team win."
Bonucci admits the midweek draw with Real Madrid was frustrating and has urged his team-mates to show "ferocity" as they look to continue their push for trophies on all fronts in 2013-14.
"We need to go further, we have to feel stronger and be more aware of our strength," said the Italy international.
"If we address them with ferocity and conviction, I'm sure we can achieve something magical."