Nerazzurri boss Andrea Stramaccioni has named an attacking line-up for the top-of-the-table encounter, with Rodrigo Palacio, Antonio Cassano and Diego Milito all selected
The Argentine replaces Gaby Mudingayi in the Nerazzurri midfield after being restricted to the role of substitute for Wednesday night's win over Sampdoria. There are also recalls for Yuto Nagatomo, who takes over from Alvaro Pereira on the left-hand side, and Juan Jesus, who replaces Fredy Guarin as Inter revert to three at the back.
The Bianconeri, meanwhile, make a total of seven changes in personnel to the side that scraped past Bologna in midweek.
Giorgio Chiellini returns alongside Andrea Barzagli and Leonardo Bonucci at the back, while Martin Caceres and Paolo De Ceglie make way for Stephan Lichtsteiner and Kwadwo Asamoah respectively on the flanks.
Paul Pogba's heroics against the Rossoblu were not enough to secure him a place in the starting lineup, with Arturo Vidal and Claudio Marchisio recalled to the midfield.
Finally, Sebastian Giovinco and Mirko Vucinic are preferred to Nicklas Bendtner and Fabio Quagliarella in attack.
Juventus: Buffon; Barzagli, Bonucci, Chiellini; Lichtsteiner, Vidal, Pirlo, Marchisio, Asamoah; Vucinic, Giovinco.
Subs: Storari, Caceres, Lucio, Isla, Marrone, De Ceglie, Padoin, Pogba, Giaccherini, Bendtner, Quagliarella, Matri.
Inter: Handanovic; Ranocchia, Samuel, Juan Jesus; Zanetti, Gargano, Cambiasso, Nagatomo; Palacio, Cassano; Milito.
Subs: Castellazzi, Belec, Silvestre, Alvarez, Guarin, Mudingayi, Pereira, Mbaye, Duncan, Livaja.