Last season's fixture left Dortmund without key players for their Champions League meeting with Malaga, and their boss is eager for a full squad to face Real Madrid
Last March, Kevin Grosskreutz, Sven Bender, Felipe Santana and Marco Reus all picked up problems in BVB's 2-1 victory at Mercedes Benz Arena, while Marcel Schmelzer was forced to wear a protective mask in the Champions League meeting with Malaga after taking a kick to the face.
With a quarter-final tie with Real Madrid looming on the horizon, Klopp is anxious to avoid a repeat of last season's scenario and ensure he has as many fit players as possible to face Carlo Ancelotti's side.
"It will be physically intense, a relegation scrap," he is quoted as saying by Bild ahead of the Stuttgart encounter. "We must adjust to the fact that there are no more friendly games.
"This is a very hard, very important phase. We hope the guys come through well. Even minor problems can mean someone is out for one or two games."