With the Three Lions eliminated from the competition, Hodgson has elected to give fringe players a chance, with Ben Foster set to start in goal, behind a back four of Phil Jones, Gary Cahill, Chris Smalling and Luke Shaw.
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As a result, Wayne Rooney and Steven Gerrard will begin the game on the bench alongside Joe Hart and Danny Welbeck.
Hodgson explained his selection at a press conference, telling reporters: "This is a chance for us to show that we can compete with this team and it is a great opportunity for a lot of the players.
"Barkley and Wilshere both have a chance to really show they are good players, playing together with a lot of other young players
"I've learned how painful it is to build hopes and see a lot of preparation come to no avail. It's unforgiving at this level. It's been a tough few days and difficult to pick yourselves up, but we'll learn a lot about the players tomorrow."
Hodgson also confirmed that Alex Oxlade-Chamberlain will play no part in the game, having failed to recover from a knee injury.
England: Foster; Jones, Cahill, Smalling, Shaw; Milner, Lampard, Wilshere, Barkley, Lallana; Sturridge