Stuart Pearce's side are set to meet Serbia at Norwich City's home ground in October, in a game which will decide whether they reach the 2013 European Championships
The Young Lions face a winner-takes-all two-legged tie against the Serbs as they look to seal their place at the 2013 edition of the tournament, which will be hosted by Israel.
The Under-21s have not featured at Carrow Road for over two years, last playing on the ground in a 1-0 win over Romania which helped seal qualification for the 2011 Euro tournament.
An attendance of 25,749 turned out to cheer Stuart Pearce's side for that game, and the FA will hope for much of the same this time around.
The game kicks off at 18.00BST on Friday October 12, with the senior team set to meet San Marino in a World Cup qualifier later that evening.
The youngsters will then fly straight out to Serbia for the return leg.