The Italian has left his post at the League One outfit after 21 months in charge at the County Ground, stating that the club have broken promises made to him over player sales
The Italian, who led the Robins to the League Two title last campaign, had previously hit out at the club's hierarchy for selling star midfielder Matt Ritchie behind his back and the former striker has now left the club after a deal for those owners to be ousted stalled too long.
A statement from Di Canio read: "Last Tuesday, 12th February, I formally confirmed my resignation as manager of Swindon Town Football Club with immediate effect.
"As I had previously stated, there have been a number of broken promises made by the club over the time that I have been Manager of Swindon Town.
"In my previous press statement on 1st February, I said that I was considering my future, as my position with the club had become untenable, after I found out that Matt Ritchie had been sold without my consent.
"Despite these problems, I have delivered everything and more that was asked of me, by achieving promotion last year as champions and competing this season for promotion to the Championship and being just three points from top place a year earlier than expected.
"I did not resign immediately, nor publicise my resignation after I had formally confirmed it, as I did not want to jeopardise the negotiations for the sale of the club and I wanted to listen to what the proposed new owners plans were.
"At the time of issuing this statement, I have had no further contact from the proposed new owners and I have been told that unfortunately Football League approval has not been granted yet and therefore my temporary arrangement has ended and my resignation stands.
"I wish the best of luck to the supporters, the players and my technical staff for the future."