Both these teams are favourites to win their respective domestic titles but Barcelona and Manchester City will clash in a Champions League group stage encounter that could be the tie of the round.
As if Pep Guardiola's return to the Nou Camp wasn't enough of a tempting wager, bet365 have announced that they will be running their ever popular risk-free in-play offer for all customers in the UK and Ireland. Full terms and conditions.
This means all players, both new and existing, will be entitled to a risk-free in-play wager which matches the stake of their biggest pre-match bet, up to £50. The picks can be on any market and there are plenty to choose from.
For example, place a pre-game bet of £25 on any market and you'll be able to place another bet once the match kicks off. If the second bet loses then your stake will be returned in cash after the final whistle. Any profits are yours to keep in cash, rollover free.
Barcelona are 8/15 (1.53) favourites to take three points from their former manager with bet365, while the same firm go 5/1 (6.0) that the Spaniard is able to beat the team that he took to two Champions League titles. The draw is a 15/4 (4.20) shot.
Goals could well flow with odds of just 2/5 (1.40) on three or more being scored. One tactic for the in-play offer could be to back the same selection twice, which would mean a £50 pre-game and in-play selection, so this bet would pay £140 instead of the usual £70. Both teams to score should also prove popular at 8/15 (1.53).
Another option for the in-play wager is to try and maximise the potential returns by backing a goalscorer bet. Lionel Messi could appeal at 8/11 (1.73) with the online firm, the same price as Neymar, while Sergio Aguero is available at 8/5 (2.60). Kevin De Bruyne has been City's star performer so far this term and the Belgium international is an 11/5 (3.20) shot to find the net.
However you choose to utilise this generous offer, it make sense to take advantage given the risk-free nature of the in-play bet and the fact that it can be scaled to accommodate all bankrolls.