Unai Emery's men went down 1-0 in Portugal last week but, having overturned a 2-0 first-leg deficit in the previous round against Real Betis, they should fancy their chances of coming out on top tonight, at odds of 10/11 (1.91) with Paddy Power.
The visitors have won just one of their five European ties on the road this season but are available at 3/1 (4.00) to seal their place in the last four with a victory this evening.
The Portuguese champions have drawn both of their away legs in this season's Europa League knockouts, and you can get odds of 13/5 (3.60) on them holding their hosts to another stalemate this time out.
Victory at the Dragao came at no small cost for Luis Castro's team, who saw midfield lynchpin Fernando and 23-goal top scorer Jackson Martinez pick up suspensions that rule them out of the trip to Spain.
Those absentees will serve to make a difficult task even more daunting, as they seek to defend their advantage against a home team that have won five of their last six games in front of their own fans.
Considering their last three home games include emphatic 4-1 victories over Real Valladolid and Espanyol plus a memorable 2-1 win over Real Madrid, los Rojiblancos will be extremely confident of overcoming a visiting side that have won just three of their last 15 on the road in all competitions.
With two of their last three trips ending in defeat, odds of 10/11 (1.91) look too good to pass up on Porto coming unstuck once again at an intimidating away ground tonight.
A key reason for Sevilla to remain confident is the form of striker Kevin Gameiro, who has struck eight goals in his last 13 games and looks rather undervalued at 2/1 (3.00) to hit the back of the net for the fifth time in this competition.
|Sevilla to win for a 2pt stake at 10/11 (1.91) with Paddy Power
||Kevin Gameiro to score anytime for a 1pt stake at 2/1 (3.00) with Paddy Power
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Al Hain-Cole is an experienced tipster and avid follower of European football. He specialises in accumulators and if you would like to read more from Al you can follow him on Twitter here.
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