The current campaign has however proved more fruitful for Los Blancos in southern Spain and they will be looking for their fifth victory in the region tonight against their in-form hosts.
Indeed Sevilla have equalled their best ever top flight run of five successive wins to move up to fifth and are capable of causing Carlo Ancelotti's men problems. Paddy Power price a home win at 9/2 (5.50) while Madrid can be backed at 4/7 (1.57).
After the disappointment of Sunday's Clasico defeat to Barcelona, nothing less than three points will do for the side from the capital, and that sheer necessity could make for an intriguing encounter.
Goals look extremely likely given that this has been one of the highest scoring fixtures in recent seasons in Spain, with 35 netted in the last six meetings.
Both teams to score is offered at just 4/9 (1.44) but Real Madrid to win and both teams to score is offered at the much more appealing price of 6/4 (2.50).
Sevilla have been in fine scoring form and are the highest scoring side in the Primera Division outside the top three. This selection has paid out in four of the last six meetings between the two sides making it an excellent option.
|Real Madrid to win and both teams to score at 6/4 (2.50) 2.0pt stake with Paddy Power|
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Phil Kitromilides is a sports journalist and TV presenter in Madrid