Both sides have a point to prove on Wednesday night but our tipster, William Duncan, is backing the Gunners' French forward to open the scoring at the Emirates Stadium
David Moyes's side suffered yet another setback on Sunday afternoon as Darren Bent's last-gasp goal rescued an unlikely point for bottom-of-the-table Fulham at Old Trafford.
With both teams keen to silence the critics, there is plenty for which to play when these two sides go head to head in north London and there is sure to be a vast array of attacking talent at both ends of the pitch.
Olivier Giroud is the top scorer for the Gunners with 10 Premier League goals thus far this term and, with United looking vulnerable at the back, having conceded in seven of their last nine matches, the France international will be keen to take advantage of any defensive frailty exhibited by the visitors.
Giroud is good value at 5/1 (6.0) with bet365 to break the deadlock for Wenger's men on Wednesday while the same firm go 6/4 (2.50) that he finds the net at any time.
The 27-year-old can be backed at 17/2 (9.50) with bet365 to score at least twice at the Emirates Stadium.
Midfielder Mesut Ozil has delivered the goods for the Gunners on occasion since arriving at the club in August but the Germany international may be a little disappointed with his return of just four league goals for Arsenal thus far this term and he has not looked at his sparkling best for the last few games.
The former Real Madrid man, though, is available at 12/1 (13.0) with bet365 to make an impact by breaking the deadlock here while bet365 offer a 4/1 (5.0) quote on Ozil finding the net at any time which could tempt value hunters searching for bigger prices.
Former Arsenal striker Robin van Persie could prove to be a key man for the Red Devils and can be backed at 5/1 (6.0) with bet365 to open the scoring against his former club. The same firm goes 6/4 (2.50) that the Dutch striker finds the net at any time during Wednesday's crunch clash.
The Netherlands international notched an impressive 96 goals in 194 appearances for Arsenal men before making his move to Manchester and the 30-year-old striker can be backed at 17/2 (9.50) with bet365 to grab the headlines by scoring at least twice on his return to north London.
Wayne Rooney is another man whom that Moyes will be hoping can grab the goals to help United to a morale-boosting win over the title-chasing side and punters may be tempted by the 13/2 (7.50) quote from bet365 for the England striker to score first on Wednesday.
The same firm offer 12/1 (13.0) for Rooney to help himself to two or more goals against the Gunners while bet365 go 2/1 (3.0) that the 28-year-old striker finds the net at any time.
The Red Devils undoubtedly boast plenty of firepower ahead of their trip to north London but Moyes's men have a soft centre that the Gunners are capable of ruthlessly exploiting.
Giroud has notched the first goal on seven occasions already this season and, therefore, it is the 5/1 (6.0) quote on offer from bet365 for the French striker to score the first goal of the game that is the recommended play for punters here.
|Olivier Giroud to score first at 5/1 (6.0) 1pt stake with bet365
Sign up with bet365 for a first deposit bonus of up to £200