On Wednesday evening Diego Simeone's men face an Austria Vienna side whom they comfortably saw off in Austria and Bet365 price a home win at the Vicente Calderon at just 1/9 (1.11).
The visitors, for their part, are the biggest price for any side in this round of Champions League matches offered at a whopping 28/1 (29.00) to record the unlikiest of victories.
Yet Atleti will almost certainly get the job done and the only question is just how big will their margin of victory be.
Austria Vienna's domestic form is in sharp contrast to that of their hosts, with Nenad Bjelica's side winning just one of their last five matches.
With Atletico scoring freely, a comfortable home vicotry is on the cards and a repeat of the 3-0 scoreline from the side's previous meeting is offered at 5/1 (6.00).
Predicting the correct score is something of a long shot
so instead backing Atletico to win with a -2 goal handicap at 5/6 (1.83) looks more infinitely more appealing.
|Atletico Madrid to win with -2 handicap at 5/6 (1.83) 2.0 point stake with bet365|
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Phil Kitromilides is a sports journalist and TV Presenter in Madrid