Queens Park Rangers are the favourites to pick up that long awaited win given their home advantage.
Despite being bottom of the league and failing to win in 10 Premier League games dating back to May, QPR are odds-on at 17/20 (1.85) with Marathon Bet to claim a vital three points.
That reflects the disappointing start that last season’s Championship winners have made to their top-flight campaign.
But Reading’s last win came at Loftus Road in the Capital One Cup in September and that could be a confidence booster for Brian McDermott’s side here.
Reading are 18/5 (4.60) to inflict further misery on Mark Hughes and grab three points from their trip to west London.
The draw that would guarantee both sides remain in the relegation zone is available at 11/4 (3.75) with Marathon Bet.
In the other markets, it is worth noting that goals seem likely given the poor defensive records of these two teams.
The Royals are yet to keep a clean sheet this season but have scored in nine of their 11 matches – including five goals in that astonishing 7-5 reverse against Arsenal on Tuesday evening.
The Hoops have fared little better – keeping one clean sheet in the Premier League but scoring in two thirds of those league games.
As a result, backing both teams to score looks a smart bet and is available at 8/13 (1.62).
But the better value can be found backing over 2.5 goals at 81/100 (1.81) with Marathon Bet.
That’s paid out in the majority of games for both sides this season and is the pick of the bets here.
For the value bet, consider that Reading have scored first in three of their last four games, while QPR have conceded first in three of their previous four matches.
Despite those statistics, Reading are a chunky 42/25 (2.68) to find the breakthrough at Loftus Road so that looks the value pick in this one.
|Over 2.5 goals at 81/100 (1.81) with Marathon
||Reading to score first at 42/25 (2.68) with Marathon|
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Adam Bate is a professional freelance journalist who specialises in football and betting. He is editor of GhostGoal which can be found here - you can also follow Adam on