Darron Gibson has withdrawn from the squad, claiming to be still recovering from the disappointment of the Euros, Shay Given has retired and Richard Dunne is absent.
It will be tough for the Republic to 'go again' given the total commitment required to make their system work.
They are 4/5 (1.80) with Paddy Power to win this one.
Trapattoni will be encouraged by the fact that Kazakhstan haven’t beaten significant opposition since a February 2009 friendly win in Estonia.
But they are not getting thumped and there have been some narrow defeats – a 2-0 loss to Belgium and a 2-1 defeat to Croatia.
Kazakhstan are 7/2 (4.50) with Paddy Power to dent Ireland’s World Cup hopes at the outset.
The better bet would surely be the draw. Kazakhstan held Austria and Latvia recently and will fancy their chances of nullifying the Irish at home. The draw is available at 5/2 (3.50).
In the goalscorers market, Robbie Keane is 4/1 (5.00) favourite to open the scoring, while the home side’s best chance of a goal is Sergei Ostapenko at 8/1 (9.00) with Paddy Power.
But the real value might be the 0-0 at 13/2 (7.50). Those Austria and Latvia games were both goalless, as were five of Ireland’s previous 14 away including the last two.
Even if Ireland do manage to find the net, we’re going under 2.5 goals here.
The visitors don’t really have the quality that would allow them to hammer Kazakhstan away and 12 of their last 17 matches have seen under 2.5 goals.
For the pick of the bets, back under 2.5 goals at 8/13 (1.62) with Paddy Power.
Watch Kazakhstan vs Ireland live on Livesport.tv
|Under 2.5 goals at 8/13 (2.62) with Paddy Power
||0-0 draw at 13/2 (7.50) with Paddy Power|
Sign up with Paddy Power for up to £250 in free bets and back Adam's selections for this game
Adam Bate is a professional freelance journalist who specialises in football and betting. He is editor of GhostGoal which can be found here - you can also follow Adam on
The road to Brazil 2014 begins here! Goal.com will be streaming Republic of Ireland's World Cup qualifier against Kazakhstan at 17:00BST via Liversport.tv on Friday. Click here to subscribe!