The Valencia boss says that the competition is on a par with their domestic league this season and also refused to discuss the current Adil Rami situation
The 47-year-old says that the European competition is very important to the Spanish club and that he knows his side must bounce back from last week's 3-0 humbling at home to Swansea City.
However, Djukic did concede that his side must still rotate players as it would be "impossible" to play the same players in back-to-back matches.
"We cannot prioritise competitions this season," he told reporters.
"The Europa League is as important as La Liga but we must still rotate players. It is impossible to play the same players in every game.
"We know we face a tough team. Russians teams are goo, and the level of their league has risen sharply in recent years. They have many players of great quality.
"Right now Swansea are the favourites to top the group but we will try and recover our lost points."
The 47-year-old refused to discuss the current situation regarding Adil Rami, however, after the Frenchman reportedly criticised his managerial skills.
"I focus on what happens right now, which is our game against Kuban," he added.