The Real Madrid attacker had to leave training due to illness and will sit out the Santiago Bernabeu showdown with BVB, and he will be replaced in the squad by Jose Rodriguez
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"Di Maria had to leave Real Madrid training today [Wednesday] due to gastroenteritis," a club statement read.
"The Argentine will be out of the match against Borussia Dortmund in the first leg of the Champions League quarter-finals.
"His position will be taken by Jose Rodriguez."
The 26-year-old Di Maria joins left-back Marcelo on the sidelines for the Santiago Bernabeu clash.