The Russians Premier League side's coach admitted they paid a "heavy price" for "simple mistakes" during their Champions League first-leg 4-2 home loss to Jurgen Klopp's men
Luciano Spalletti slammed his side's lack of concentration as Zenit fell to a 4-2 defeat against Borussia Dortmund in the Champions League on Tuesday.
The Italian head coach saw his Russian Premier League leaders recover from the shock of conceding two early goals by halving the deficit 12 minutes into the second half.
However, just four minutes after Oleg Shatov had scored, Zenit allowed Robert Lewandowski to restore Dortmund's two-goal advantage - and when Hulk converted a penalty in the 69th minute they again switched off, allowing the Polish striker to grab his second within two minutes.
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"What bothers me the most - it's the moments in which we make naive and simple mistakes," he said. "Unfortunately, with our team, it happens. In some episodes we lose concentration.
"I believe that in our game, there are moments when we lose a high level of concentration and allow unforced errors, but at this level you pay a heavy price."
Although they face a daunting task in Dortmund on March 19, Spalletti insisted that they could still prevail.
"We go there to play with the hope of further output," the Italian added. "In football, as in any other sport game, there is always the opportunity to turn around even the most difficult result.
"It all depends on what you're willing to give in order to achieve results.
"From the perspective of skill, strength, willingness to work, desire to run, the volume of this work.
"Everything is possible. Everything depends on you."