The match-winner against West Brom is rewarded for his two-goal display with a starting berth up front alongside Sergio Aguero the crucial Champions League Group D tie
The Bosnian netted both goals in his side's dramatic 2-1 turnaround against the Baggies and starts up front alongside fellow recalled front-man Sergio Aguero, with Carlos Tevez and Mario Balotelli dropping to the bench.
James Milner will be hoping to impress Mancini after his first-half red card at the Hawthrosn meant that City had to play much of the match with 10 men.
City are desperate for three points after a 3-2 loss away to Real Madrid and a last-gasp 1-1 draw at home to Borussia Dortmund left them with just one point from their opening two group-stage games.
As for the hosts, highly rated playmaker Christian Eriksen will be expected to perform as the Dutch giants look for their first points of the group stages.
Ajax starting XI: Vermeer; Alderweireld, Moisander, Blind, Van Rhijn, C Poulsen, Eriksen, De Jong, Schone, Sana, Babel
Subs: Cillessen, Enoh, Sulejmani, Boerrigter, Veltman, Dijks, Fischer
Manchester City XI: Hart; Richards, Kompany, Lescott, Clichy; Milner, Barry; Nasri, Yaya Toure; Aguero, Dzeko
Subs: Pantilimon, Kolarov, Nastasic, Evans, Sinclair, Tevez, Balotelli